Vascular Medicine Conference-CVC 2026

Chronic Limb Ischemia (CLI) represents a serious, progressive condition characterized by significantly diminished blood flow to the lower extremities, typically as a result of advanced peripheral artery disease. Unlike its acute counterpart, CLI develops over time, often manifesting as persistent rest pain, non-healing ulcers, gangrene, or even tissue loss. Key risk factors include diabetes, tobacco use, hypertension, hypercholesterolemia, and advancing age. Recognizing the condition early is crucial to minimize complications and preserve limb function.

Effective management of CLI centers on reestablishing adequate circulation, alleviating pain, and reducing the risk of limb loss. Therapeutic strategies may involve pharmacological intervention, lifestyle modification, and revascularization procedures—either through endovascular techniques or surgical bypass. For individuals presenting with ulcers or gangrene, meticulous wound care and rigorous infection prevention are imperative. With prompt medical attention, ongoing surveillance, and diligent risk factor control, patients have the potential to improve mobility, decrease the likelihood of amputation, and enhance overall vascular health.