Drug-coated peripheral devices are cutting-edge tools used in endovascular procedures to tackle peripheral artery disease by delivering medication straight to the arterial wall. These devices, which include drug-coated balloons and drug-eluting stents, work to prevent neointimal hyperplasia, thereby lowering the chances of restenosis and enhancing long-term vessel patency.By utilizing these devices, healthcare professionals can perform minimally invasive vascular interventions more effectively, treating complex lesions while keeping procedural complications to a minimum. The integration of imaging technologies ensures precise placement, and ongoing clinical studies are focused on refining drug formulations and device designs. Overall, drug-coated peripheral devices mark a major leap forward in vascular therapy, providing better outcomes and a higher quality of life for patients dealing with peripheral artery disease.