Stem cell therapy has been attracting considerable attention as a novel approach in regenerative medicine, particularly for vascular repair and regeneration. By employing stem cells sourced from bone marrow, adipose tissue, or umbilical cord, clinicians aim to promote angiogenesis, restore blood flow, and support tissue repair in conditions such as peripheral artery disease, myocardial ischemia, and chronic wounds.
These stem cells exhibit multiple mechanisms of action: they can differentiate into endothelial cells, release critical growth factors, and modulate inflammatory responses, collectively contributing to improved vascular function. Emerging clinical research suggests that stem cell therapy may enhance limb perfusion, alleviate pain, and accelerate wound healing in patients suffering from critical limb ischemia. Delivery methods vary, with intramuscular and intra-arterial injections being tailored to disease severity and tissue requirements.
Despite these promising developments, stem cell therapy remains under active investigation. Questions about long-term efficacy and safety persist, and additional research is needed before widespread adoption. Integrating stem cell therapy with established treatments—such as revascularization procedures or pharmacological interventions—could further optimize clinical outcomes. As advancements continue, stem cell therapy holds significant promise for transforming the treatment landscape for vascular diseases, with the potential to markedly improve patient quality of life.