MicroRNAs, or miRNAs for short, are tiny non-coding RNA molecules that play a vital role in regulating gene expression and keeping our vascular system healthy. They have a significant impact on how endothelial cells function, how smooth muscle cells behave, and how our bodies respond to inflammation—all crucial for ensuring our blood vessels work properly. When certain miRNAs go awry, it can lead to vascular issues like atherosclerosis, hypertension, and restenosis.
Studying miRNAs opens up exciting possibilities for their use as diagnostic tools and treatment targets. By measuring circulating miRNAs, we can gain valuable insights into endothelial dysfunction, track how diseases progress, and even predict cardiovascular risks. The therapeutic manipulation of miRNAs is a promising new field focused on restoring balance in our vascular system, reducing inflammation, and ultimately improving the health outcomes for those dealing with vascular disorders