Vascular Medicine Conference-CVC 2026

Pulmonary embolism, often abbreviated as PE, happens when a blood clot—most commonly one that originated as a deep vein thrombosis (DVT) in the leg—travels to the lungs and blocks blood flow. This can cause abrupt shortness of breath, chest pain, a rapid heart rate, coughing, and, in severe circumstances, collapse or even sudden death. Risk factors are numerous and include prolonged immobility (think long flights or hospital stays), recent surgery, malignancy, pregnancy, obesity, and inherited clotting disorders. Recognizing PE early and starting treatment promptly are crucial to reducing the risk of life-threatening complications.

Treatment centers on dissolving the existing clot or preventing new ones from forming, while maintaining sufficient blood flow. Anticoagulant medications, or blood thinners, are the mainstay of therapy. In more severe cases, thrombolytic drugs or surgical interventions may be necessary. Supportive care—such as oxygen supplementation and close clinical monitoring—is also important. Long-term management focuses on addressing underlying risk factors, preventing recurrence, and ensuring patients receive appropriate follow-up care to minimize the chance of future embolic events.