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Vascular Medicine Conference-CVC 2026

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Thrombophilia Screening

Thrombophilia screening is all about running lab tests to find out if someone has inherited or acquired conditions that could lead to abnormal blood clots. Some common inherited thrombophilias include the Factor V Leiden mutation, prothrombin gene mutation, and deficiencies in proteins C, S, or antithrombin. We also look at acquired causes like antiphospholipid syndrome. This screening is especially important for patients who have had recurrent venous thromboembolism, unexplained clots, or a strong family history of thrombosis.

When it comes to lab evaluations, we typically conduct coagulation assays, genetic tests, and antibody screenings. Catching a hypercoagulable state early on allows doctors to put preventive measures in place, whether that’s through anticoagulation therapy or lifestyle changes, which can help lower the chances of recurrent thrombosis and boost long-term vascular health. Tailoring management based on screening results really enhances safety and outcomes for those at high risk.

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